科研亮点
科学日报专题报导香港分部主任钱培元教授领衔的深海生物研究成果
Genomic secrets of scaly-foot snail from hydrothermal vents: Laying foundation for potential solutions provided by deep-sea creatures
Journal Reference:
Jin Sun, Chong Chen, Norio Miyamoto, Runsheng Li, Julia D. Sigwart, Ting Xu, Yanan Sun, Wai Chuen Wong, Jack C. H. Ip, Weipeng Zhang, Yi Lan, Dass Bissessur, Tomo-o Watsuji, Hiromi Kayama Watanabe, Yoshihiro Takaki, Kazuho Ikeo, Nobuyuki Fujii, Kazutoshi Yoshitake, Jian-Wen Qiu, Ken Takai, Pei-Yuan Qian. The Scaly-foot Snail genome and implications for the origins of biomineralised armour. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-15522-3
科学日报专题报导香港分部主任钱培元教授领衔的活性物质的研究成果
Researchers unlock cancer-causing mechanism of E. coli toxin with synthetic biology approach
Journal Reference:
Zhong-Rui Li, Jie Li, Wenlong Cai, Jennifer Y. H. Lai, Shaun M. K. McKinnie, Wei-Peng Zhang, Bradley S. Moore, Wenjun Zhang, Pei-Yuan Qian. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. Nature Chemistry, 2019; DOI: 10.1038/s41557-019-0317-7
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专利和许可
香港分部有1项已申请的国家专利以及1项已申请的国际专利。同时,香港分部亦申请了5项国家专利,3项国际专利,5项美国临时专利。
国家专利
- "椭圆状对插型阵列电极及其柔性检测系统",申请公布号为CN211955304U。
- "一种将糠醇氧化为二氢吡喃酮类的绿色方法",专利申请号为202110081888。
- "一种制备氧化吲哚类衍生物的绿色方法",专利申请号为202110206801。
- "一种绿色的溴化方法",专利申请号为202110199168.X。
- "作为针对各种神经退行性疾病的潜在治疗剂的新化合物",专利申请号为202111078152.X。
国际专利
- "Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining"。
- “Adenine deficient yeast: A fluorescent biosensor for the detection of Labile Zn (II) in aqueous solution”。
- “Novel compounds as potential therapeutic agents targeting various neurodegenerative diseases”
美国临时专利
- "Amperometric electrochemical sensor for the detection of small molecules"。
- "BOC-Butenolide, an antifouling compound that has potent ability to inhibit the settlement of marine invertebrate larvae"。
- “Albofungin and its derivatives specific bind with HIV-1 LTR-III G-quadruplex”。
- “Potent antifouling compounds albofungins target multiple fouling organisms”。
- "Albofungin and its derivatives specifically recognize HIV-1 LTR-III G-quadruplex"。
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